Which dessert is primarily made using espresso and mascarpone cheese?

Tiramisu is the dessert that is primarily made using espresso and mascarpone cheese. This classic Italian dessert features layers of coffee-soaked ladyfingers and a rich mascarpone cream, which is often flavored with cocoa and sometimes includes a hint of rum or Marsala wine. The combination of the strong coffee flavor from the espresso and the creamy, smooth texture of the mascarpone creates a distinctive taste that is both indulgent and satisfying.

In contrast, cheesecake is primarily made with cream cheese or ricotta, panna cotta is a creamy dessert thickened with gelatin, and gelato is a frozen dessert similar to ice cream but with a different base and generally less air incorporated. These alternatives do not showcase the unique combination of espresso and mascarpone that defines tiramisu, making it the clear answer in this context.